Aloevera and Inflammation: An Examination of its Role in Inflammatory Conditions
Aloe vera, a succulent plant native to Africa, has been used for centuries for its medicinal properties. The gel extracted from the leaves is known for its soothing effects on skin irritations and burns. However, recent research suggests that aloe vera might also have potential benefits in managing inflammation.
Numerous studies have been conducted to investigate the anti-inflammatory effects of aloe vera. According to a study published in the Journal of Ethnopharmacology (2015), aloe vera contains compounds such as anthraquinones, aloesin, and salicylic acid, which exhibit anti-inflammatory activities.
The anti-inflammatory properties of aloe vera are believed to be due to its ability to inhibit the release of pro-inflammatory cytokines and enzymes, such as cyclooxygenase-2 (COX-2), lipoxygenase, and nitric oxide synthase (NOS) (Sharma et al., 2015). By inhibiting these enzymes, aloe vera may help reduce inflammation, pain, and swelling associated with various conditions.
While more research is needed to fully understand the potential benefits of aloe vera for inflammatory conditions, existing evidence suggests that it may have anti-inflammatory properties. It is essential to note that while aloe vera may offer relief, it should not replace professional medical treatment for chronic or severe inflammation.
References
1. Sharma, R., Gupta, S., & Baishya, P. K. (2015). Aloe vera: A short review on pharmacological activities and therapeutic uses. Journal of Pharmacognosy and Phytochemistry, 3(6), 767–774.
2. Al-Zuhair, M., Abd El-Rahman, H. A., Mohamed, E. N., & Abou-Donia, M. B. (2015). Antioxidative and anti-inflammatory activities of methanolic extract of aloe vera leaves. Journal of Ethnopharmacology, 172(3), 648–655.
3. Kim, J., Lee, S. K., Park, H. J., & Choi, J. Y. (2017). Inhibitory effect of aloe vera on inflammatory mediators and COX-2 expression in lipopolysaccharide-induced RAW 264.7 cells. Journal of Medicinal Food, 20(3), 338–345.